Johann Berg Gudmundsson is set for an extended spell on the sidelines after being injured on international duty.
Gudmundsson damaged a hamstring in Iceland’s Euro qualifying defeat to France last Friday.
And Burnley boss Sean Dyche is resigned to being without the winger – who started his first club game since August as the Clarets beat Everton ahead of the international break – for a number of weeks.
“Unfortunately, he got injured on international duty and a reasonably serious hamstring injury,” confirmed Dyche.
“It certainly won’t be days. It will be more like weeks. I don’t know how many yet but it’s serious enough to speak in that way.”
Jack Cork is also still a doubt for Saturday's trip to Leicester City after missing his first Premier League game for 11 months against the Toffees with the shoulder blade fracture he sustained at Aston Villa at the end of September.
Erik Pieters has been passed fit to face the Foxes
And striker Ashley Barnes will also have a fitness check on a tight groin ahead of the visit to the King Power Stadium, which will come too soon for Danny Drinkwater to face his former club as the on-loan midfielder continues to recover from an ankle injury.
The Clarets could therefore find themselves without a couple of key men as they look to extend their unbeaten four-match run against the fourth-placed Foxes.
But Dyche believes his current squad - just two points behind Leicester in seventh spot - is well equipped to deal with any absences, given the added strength in depth at his disposal.
“I’ve had groups with individuals in and groups who have performed fantastically well over my time here," added the Clarets' chief, who confirmed that ever-present full-back Erik Pieters has recovered from the leg injury that forced him to come off during the 2-0 win over Everton.
“But if I look at a group of players for every position, where I honestly believe any player could play at any given time, then this is the closest we’ve ever had it.
“I think there’s a real fine margin between who’s got a shirt and who hasn’t at the moment and I think that’s a healthy position to be in.
“It doesn’t guarantee anything, but I think that enhances your performance levels because everyone is looking over their shoulder.”