The U18s travel to fourth placed Leeds United this weekend, where the Clarets can rise to second with a victory if Nottingham Forest fail to win.
Burnley enjoyed a 6-1-win last weekend at home to Crewe Alexandra, where 15-year old striker Lewis Richardson hit five on his first start for the club.
United lost 4-1 won last time out, however, the Yorkshire side have only lost four times this season.
The two sides faced each other three times last season.
The Clarets took all three points in the home fixture and knocked United out of the FA Youth Cup just three days later.
However, in the game at Leeds’ Thorpe Arch the hosts took all three points in a 4-2 win.
The match kicks off at 11:00am at Thorpe Arch, live updates will be available on Twitter (@Burnleyofficial) followed by reaction and report.