Jon Walters has been ruled out of the Republic of Ireland’s make-or-break World Cup qualifiers.
Ireland manager Martin O’Neil confirmed the Clarets’ striker will miss the games against Moldova and Wales next month with a knee injury.
Walters has missed Burnley’s last two games with the problem.
Turf Moor team-mates Jeff Hendrick, Robbie Brady, Stephen Ward and Kevin Long are included in a provisional 32-man squad, with Hendrick returning after recovering from the thigh injury which kept him out of Ireland’s last two games in Group D.
Brady is suspended for the match against Moldova in Dublin on Friday, 6 October, but will be available to face Wales and Burnley team-mate Sam Vokes in Cardiff three days later in a game that could decide who finishes second in the group and potentially secures a play-off place.
The absence of the experienced Walters is a blow for Ireland, who are likely to need to win both games to keep alive their hopes of reaching the 2018 finals in Russia.
Capped 51 times by his country, Burnley’s summer signing has scored 14 times for Ireland and has captained the side during the current qualifying campaign.
Republic of Ireland squad:
Goalkeepers: Randolph (Middlesbrough), Westwood (Sheffield Wednesday), Elliot (Newcastle), Doyle (Bradford)
Defenders: Christie (Middlesbrough), Keogh (Derby), Duffy (Brighton), Clark (Newcastle), O'Shea (Sunderland), Long (Burnley), Ward (Burnley)
Midfielders: McGeady (Sunderland), McClean (West Brom - suspended for Moldova game), Whelan (Aston Villa), Hourihane (Aston Villa), Hendrick (Burnley), Brady (Burnley - suspended for Moldova game), McCarthy (Everton), Meyler (Hull), Arter (Bournemouth), O'Kane (Leeds), Hoolahan (Norwich), Hayes (Celtic), O'Dowda (Bristol City), Horgan (Preston)
Strikers: Long (Southampton), Murphy (Nottingham Forest), McGoldrick (Ipswich), Doyle (Colorado Rapids), Maguire (Preston), Hogan (Aston Villa), O'Brien (Millwall).