Burnley go into the game having extended their unbeaten run to five games after a 0-0 draw against Derby County at the iPro Stadium on Monday.
The Clarets were resolute in face of second-half pressure from the hosts and moved up to third in the Sky Bet Championship.
Striker Andre Gray was substituted with a hamstring problem, and boss Sean Dyche will make a late decision on his fitness ahead of this weekend.
Meanwhile, Reading go into the game on the back of a narrow Capital One Cup defeat to Everton on Tuesday.
Nick Blackman gave the Royals the lead when he met Ola John’s cross, before goals from Ross Barkley and Gerard Deulofeu saw the Premier League side progress.
Steve Clarke’s men have started well in the Sky Bet Championship, recently beating Brentford and Bristol City away from home and defeating Ipswich 5-1 at the Madjeski Stadium. Their only league defeat in September came at home to Burnley’s last opponents Derby.
Czech international striker Matej Vydra has joined Reading on a season-long from Premier League Watford.
The 23-year-old has a proven track record of netting in the Championship after registering 22 goals in his first loan spell with the Hornets.
And he scored another 16 goals on the way to promotion last season at Vicarage Road. Vydra has worked under boss Steve Clarke before during a loan spell at West Bromwich Albion.
Reading (Trippier o.g. 16’, McCleary 58’) 2-2 Burnley (Arfield 20’, Ings 28’)
Burnley: Heaton, Trippier, Duff, Shackell, Mee, Arfield (Stanislas, 71), Marney, Jones, Kightly (Wallace, 63), Ings, Barnes.
Subs not used: Cisak, Long, Baird, Edgar, Treacy.
Reading: McCarthy, Gunter, Pearce, Pogrebnyak, Leigertwood, Le Fondre (Robson-Kanu, 57), McAnuff, McCleary, Morrison, Akpan (Taylor,55), Obita.
Subs not used: Federici, Gorkss, Blackman, Cummings, Hector.
Attendance: 23, 335 (2,021 Visitors)
Sean Dyche will make a late decision on the fitness of Andre Gray after the striker limped out of the game against Derby County with a hamstring injury.
Joey Barton is in contention again after making the bench at the iPro Stadium for the first time and playing 90 minutes against Hartlepool in the week at Gawthorpe and scoring.
Fredrik Ulvestad also featured in that game against Hartlepool as he steps up a return from an ankle injury and played 90 minutes in the 3-3 draw against Fleetwood Town.
Dean Marney and Kevin Long continue to get minutes under their belt as they edge closer to a return from cruciate ligament injuries.
Tony Harrington will take charge of Saturday’s home Sky Bet Championship fixture against Reading.
The official from Cleveland has officiated 4 games in the 2015/16 season so far, producing 11 yellow cards in the process and no reds.
The last Burnley game he took charge of was also at Turf Moor, when the Clarets beat Doncaster Rovers 2-0 courtesy of goals from Sam Vokes and Junior Stanislas.
Three players were booked on that day, Dean Marney for the Clarets and two for the visitors.
Mr Harrington will be assisted by Mr B Cropp, Mr A Clayton and Fourth Official Darren Bond.
Sean Dyche: “They’ve had some good results. We know there is no easy ride in the Championship and we have to be prepared for every game, every half even.
“Home form is an important thing because we want our fans to enjoy what we’re doing, we want them to be part of it and winning always helps that.”
Steve Clarke: “Burnley will be strong, solid, well-organised and difficult to beat,”
“They have started the season well – sometimes there is a little bounce effect when you get relegated, and you don’t start so well, but Sean and his team have started the season well and we’re looking forward a really difficult game.”
Burnley are the 5/4 favourites with Sky Bet for victory at home to Reading in the Sky Bet Championship on Saturday afternoon. The Royals are outsiders at 11/5 to win and the draw is on offer at 23/10.
The Clarets drew 0-0 at Derby on Monday night and another goalless encounter can be supported at 17/2 with Sky Bet. You can also get 8/11 with Sky Bet for under 2.5 goals to be scored at Turf Moor.
Sky Bet offer 21/10 for Burnley to win 1-0, 2-0 or 2-1 in their Correct Score Group Betting.
Sign up here: www.skybet.com/fl72