The Clarets made it three successive wins in the U18 Professional Development League with victory over Leeds United taking them top of the table.
The two sides meet again in the FA Youth Cup at Turf Moor on Monday night when the Clarets are likely to have a much-changed line-up.
But the youthful team led for Saturday's league encounter by assistant coach John Townson - with only three players who started last week's victory at Nottingham Forest included - did their job thanks to a winner from the penalty spot from under-16s striker Mitchell George.
Burnley took the lead just before the break throughTerry Mupariwa before Leeds leveled 10 minutes in to the second half through a spectacular free-kick.
But George stepped up to the physical challenge of playing in the older age group and after being brought down in the area picked himself up to slot home and bag the points.
The Clarets started off well and came close when Dylan Meredith’s free-kick rattled off the post.
And just before half-time, Mupariwa picked up the ball just outside the area and drilled home into the bottom corner to give Burnley the lead.
Leeds didn’t hang about in search of an equaliser and just after the break pulled the scores level with a sweet strike from a free-kick 30 yards out.
Burnley were then gifted a glorious opportunity to go back in front when George broke through on goal before striking inches wide.
But the lively forward was in again minutes later and was brought down in the area by the Leeds goalkeeper.
Up the youngster stepped and put the ball into the bottom corner to give Burnley the advantage with just over 10 minutes to go.
And the Clarets kept Leeds out with confidence in the dying moments, ensuring all three points and striking a blow ahead of Monday’s third-round cup clash.
Burnley: Wusiewicz, Badhawi (Taylor 50), Mpofu (Rain 45), Conely, Thomas, King, Tucker, Mupariwa, Ellison, George, Meredith (Major 86). Subs: Calderbank-Park, Samms.