The Clarets face another big night at Turf Moor as they look to pull off a landmark result and climb out of the Premier League’s bottom three.
Sean Dyche’s men beat Liverpool on their own ground two years ago and last season were only seconds away from taking a point when the two sides met on New Year’s Day.
That followed a 1-1 draw at Anfield earlier in the season as the Clarets made a flying start to a historic campaign.
Burnley are yet to hit those heights again this term, while the Reds – who boast the best defensive record in the top flight – are unbeaten in the league as they look to stay in touch with champions and leaders Manchester City.
Jurgen Klopp’s side will also arrive in East Lancashire on a high following their last-gasp derby-day win over Everton on Sunday.
Sam Vokes scored his first Premier League goal to help beat Liverpool
But Burnley have upset the big guns before.
And a repeat of the point they took from City on their march to the title last season will be enough to lift the Clarets out of the drop-zone, with Dyche looking to the fans to play their part in Burnley’s bid to beat the odds and potentially kick-start a revival.
“We have had our fair share of results playing against these sides,” said the Burnley boss.
“The stats show how difficult it is playing against these sides – not just Liverpool but all the top six.
“But everyone loves an underdog story and everyone loves someone to beat someone they shouldn’t.
“The fans outside Liverpool want that and the Burnley fans definitely want that.
“It’s a mentality and a belief system and going in and delivering a performance in the right manner.
“It’s a crowd getting behind the team and that connecting thing we’ve had many, many times here at Turf Moor.
“Even though we went down in the game against Newcastle, the fans were absolutely fantastic. It was one of the highest-energy atmospheres we’ve had there for a long time. That is a really important factor.
“You need all of that and you still need a good performance and, when you play the big boys, you sometimes need the rub of the green.”
Steven Defour is an injury doubt for the Clarets with a slight knee problem.
Liverpool are expected to make changes after Sunday’s Merseyside derby and with a make-or-break Champions League group decider against Napoli less than a week away.
Forward Sadio Mane is set to miss out with a cut foot and left-back Andy Robertson is among those expected to be given a breather.
Divock Origi (above) could earn a start after his dramatic late winner against Everton.
Captain Jordan Henderson is back from suspension and expected to make his 300th career league appearance.
The Clarets are looking to end a seven-match winless run and secure a first home victory since September.
Liverpool are unbeaten in the Premier League and have won five of their last six games.
They haven’t travelled well in Europe with defeats in all three of their away group games in the Champions League.
Liverpool manager Jurgen Klopp: “The Burnley squad is strong and I know they will be fine in the end of the season, I am sure.
“They look calm in the moment and so far they didn’t get the results they maybe would have deserved with their performances.
“Now we have to make sure their run starts at the earliest at the weekend and not earlier.”
Burnley boss Sean Dyche takes charge of his 300th league game as a manager – 46 with Watford and 254 with the Clarets.
Liverpool are chasing a win that would give them their highest ever points’ tally after 15 games of a season.
All of Liverpool’s seven goals at Turf Moor in the Premier League have come in the second half of matches.
The Reds have won only one of their last seven away games against teams in the relegation zone.